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Single-dose tumor necrosis factor protection against endotoxin-induced shock and tissue injury in rats.

Tumor necrosis factor (TNF), a macrophage product released in response to endotoxin and other stimuli, has been shown to be a central mediator of endotoxin or septic shock. However, its highly conserved and wide-ranging physiological effects suggest that it may also be an essential cytokine in the h...

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Autors principals: Alexander, H R, Doherty, G M, Block, M I, Kragel, P J, Jensen, J C, Langstein, H N, Walker, E, Norton, J A
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC258973/
https://ncbi.nlm.nih.gov/pubmed/1937748
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