Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity.

We synthesized Cryptococcus neoformans serotype A glucuronoxylomannan (GXM) conjugate vaccines under conditions suitable for human use to prevent disseminated cryptococcosis. The purified, sonicated GXM was derivatized with adipic acid dihydrazide through either hydroxyl or carboxyl groups and then...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Devi, S J, Schneerson, R, Egan, W, Ulrich, T J, Bryla, D, Robbins, J B, Bennett, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3700-3707.1991
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