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Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity.

We synthesized Cryptococcus neoformans serotype A glucuronoxylomannan (GXM) conjugate vaccines under conditions suitable for human use to prevent disseminated cryptococcosis. The purified, sonicated GXM was derivatized with adipic acid dihydrazide through either hydroxyl or carboxyl groups and then...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Devi, S J, Schneerson, R, Egan, W, Ulrich, T J, Bryla, D, Robbins, J B, Bennett, J E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3700-3707.1991
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