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Acid stress damage of DNA is prevented by Dps binding in Escherichia coli O157:H7

BACKGROUND: Acid tolerance in Escherichia coli O157:H7 contributes to persistence in its bovine host and is thought to promote passage through the gastric barrier of humans. Dps (DNA-binding protein in starved cells) mutants of E. coli have reduced acid tolerance when compared to the parent strain a...

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Main Authors: Jeong, Kwang Cheol, Hung, Kai Foong, Baumler, David J, Byrd, Jeffrey J, Kaspar, Charles W
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588596/
https://ncbi.nlm.nih.gov/pubmed/18922164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-181
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