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Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection

Neonatal Borna disease virus (BDV) infection of the rat brain is associated with microglial activation and damage to certain neuronal populations. Since persistent BDV infection of neurons is nonlytic in vitro, activated microglia have been suggested to be responsible for neuronal cell death in vivo...

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Bibliografiske detaljer
Main Authors: Ovanesov, Mikhail V, Ayhan, Yavuz, Wolbert, Candie, Moldovan, Krisztina, Sauder, Christian, Pletnikov, Mikhail V
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588577/
https://ncbi.nlm.nih.gov/pubmed/19014432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-50
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