Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus

Neonatal Borna Disease Virus (BDV) infection in rats leads to a neuronal loss in the cortex, hippocampus and cerebellum. Since BDV is a non-lytic infection in vitro, it has been suggested that activated microglia could contribute to neuronal damage. It is also conceivable that BDV-induced cell death...

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Detalhes bibliográficos
Main Authors: Ovanesov, Mikhail V, Moldovan, Krisztina, Smith, Kimberly, Vogel, Michael W, Pletnikov, Mikhail V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397384/
https://ncbi.nlm.nih.gov/pubmed/18489759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-16
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