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Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination

Recently Mycobacterium tuberculosis was shown to possess a novel protein modification, in which a small protein Pup is conjugated to the epsilon-amino groups of lysines in target proteins. Analogous to ubiquitin modification in eukaryotes, this remarkable modification recruits proteins for degradati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iyer, Lakshminarayan M, Burroughs, AM, Aravind, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588565/
https://ncbi.nlm.nih.gov/pubmed/18980670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-3-45
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