Inhibition of the alternative C3 convertase and classical C5 convertase of complement by group A streptococcal M protein.

When Streptococcus pyogenes group A type 3 strain C203 (M+) and its M-protein-lacking derivative, strain C203S (M-), were treated with normal human serum in the presence of magnesium-EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid], virulent M+ bacteria bound only 10 to 3...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Hong, K, Kinoshita, T, Takeda, J, Kozono, H, Pramoonjago, P, Kim, Y U, Inoue, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2142480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.8.2535-2541.1990
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