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Inhibition of the alternative C3 convertase and classical C5 convertase of complement by group A streptococcal M protein.

When Streptococcus pyogenes group A type 3 strain C203 (M+) and its M-protein-lacking derivative, strain C203S (M-), were treated with normal human serum in the presence of magnesium-EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid], virulent M+ bacteria bound on...

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Detalhes bibliográficos
Main Authors: Hong, K, Kinoshita, T, Takeda, J, Kozono, H, Pramoonjago, P, Kim, Y U, Inoue, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC258852/
https://ncbi.nlm.nih.gov/pubmed/2142480
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