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Regulating amyloid precursor protein synthesis through an internal ribosomal entry site

Expression of amyloid precursor protein (APP) is critical to the etiology of Alzheimer's disease (AD). Consequently, regulating APP expression is one approach to block disease progression. To this end, APP can be targeted at the levels of transcription, translation, and protein stability. Littl...

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Detalhes bibliográficos
Main Authors: Beaudoin, Monique E., Poirel, Vincent-Joseph, Krushel, Leslie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588504/
https://ncbi.nlm.nih.gov/pubmed/18953033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn792
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