Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

Although activated spinal cord glia contribute importantly to neuropathic pain, how nerve injury activates glia remains controversial. It has recently been proposed, on the basis of genetic approaches, that toll-like receptor 4 (TLR4) may be a key receptor for initiating microglial activation follow...

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Détails bibliographiques
Auteurs principaux: Hutchinson, Mark R., Zhang, Yingning, Brown, Kimberley, Coats, Benjamen D., Shridhar, Mitesh, Sholar, Paige W., Patel, Sonica J., Crysdale, Nicole Y., Harrison, Jacqueline A., Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588470/
https://ncbi.nlm.nih.gov/pubmed/18662331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06321.x
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