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An A(2A )adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

BACKGROUND: The pathophysiology of sepsis is due in part to early systemic inflammation. Here we describe molecular and cellular responses, as well as survival, in A(2A )adenosine receptor (AR) agonist treated and untreated animals during experimental sepsis. METHODS: Sepsis was induced in mice by i...

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Detalhes bibliográficos
Main Authors: Moore, Christopher C, Martin, Edward N, Lee, Grace H, Obrig, Tom, Linden, Joel, Scheld, W Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588444/
https://ncbi.nlm.nih.gov/pubmed/18937852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-8-141
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