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Homeostatic expansion of CD4(+) T cells upregulates VLA-4 and exacerbates HSV induced corneal immunopathology

Using a viral induced immunopathology model, we showed that when CD4(+) T cells were allowed to undergo homeostatic expansion prior to ocular HSV infection, mice developed more severe inflammatory lesions with the increased severity associated with enhanced effector function of ocular CD4(+) T cells...

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Sonraí Bibleagrafaíochta
Main Authors: Suvas, Susmit, Kim, Bumseok, Rouse, Barry T
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588139/
https://ncbi.nlm.nih.gov/pubmed/18657630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.06.012
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