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Homeostatic expansion of CD4(+) T cells upregulates VLA-4 and exacerbates HSV induced corneal immunopathology
Using a viral induced immunopathology model, we showed that when CD4(+) T cells were allowed to undergo homeostatic expansion prior to ocular HSV infection, mice developed more severe inflammatory lesions with the increased severity associated with enhanced effector function of ocular CD4(+) T cells...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2588139/ https://ncbi.nlm.nih.gov/pubmed/18657630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.06.012 |
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