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In Vitro-Generated Antigen-Specific CD4(+) CD25(+) Foxp3(+) Regulatory T Cells Control the Severity of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions

Generating and using regulatory T cells (Tregs) to modulate inflammatory disease represents a valuable approach to therapy but has not yet been applied as a means to control virus-induced immunopathological reactions. In this report, we developed a simplified technique that used unfractionated splen...

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Autors principals: Sehrawat, Sharvan, Suvas, Susmit, Sarangi, Pranita P., Suryawanshi, Amol, Rouse, Barry T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446952/
https://ncbi.nlm.nih.gov/pubmed/18480441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00697-08
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