Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

Inflammation can extend ischemic brain injury and adversely affect outcome in experimental animal models. A key difficulty in translating animal studies to humans is the lack of a definitive method to confirm and track inflammation in the brain in vivo. Myeloperoxidase (MPO), a key inflammatory enzy...

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Bibliographic Details
Main Authors: Breckwoldt, Michael O., Chen, John W., Stangenberg, Lars, Aikawa, Elena, Rodriguez, Elisenda, Qiu, Shumei, Moskowitz, Michael A., Weissleder, Ralph
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587593/
https://ncbi.nlm.nih.gov/pubmed/19011099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803945105
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