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Measuring internal friction of an ultrafast-folding protein

Nanosecond laser T-jump was used to measure the viscosity dependence of the folding kinetics of the villin subdomain under conditions where the viscogen has no effect on its equilibrium properties. The dependence of the unfolding/refolding relaxation time on solvent viscosity indicates a major contr...

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Detalhes bibliográficos
Main Authors: Cellmer, Troy, Henry, Eric R., Hofrichter, James, Eaton, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587570/
https://ncbi.nlm.nih.gov/pubmed/19020085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806154105
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