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Stepwise evolution of protein native structure with electrospray into the gas phase, 10(−12) to 10(2) s

Mass spectrometry (MS) has been revolutionized by electrospray ionization (ESI), which is sufficiently “gentle” to introduce nonvolatile biomolecules such as proteins and nucleic acids (RNA or DNA) into the gas phase without breaking covalent bonds. Although in some cases noncovalent bonding can be...

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Bibliografiska uppgifter
Huvudupphovsmän: Breuker, Kathrin, McLafferty, Fred W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587555/
https://ncbi.nlm.nih.gov/pubmed/19033474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807005105
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