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Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing VEGFR2 signaling

Gambogic acid (GA), the main active compound of Gamboge Hanburyi, has been previously reported to activate apoptosis in many types of cancer cell lines by targeting transferrin receptor and modulating NF-kappa B signaling pathway. Whether GA inhibits angiogenesis, which is crucial for cancer and oth...

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Detalhes bibliográficos
Main Authors: Yi, Tingfang, Yi, Zhengfang, Cho, Sung-Gook, Luo, Jian, Pandey, Manoj K., Aggarwal, Bharat B., Liu, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587446/
https://ncbi.nlm.nih.gov/pubmed/18339865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5944
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