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Translation factors promote formation of two states of the closed loop mRNP

Efficient translation initiation and optimal stability of most eukaryotic mRNAs depends on the formation of a closed loop structure and the resulting synergistic interplay between the 5′ m7G cap and the 3′ poly(A) tail1,2. Evidence of eIF4G and Pab1p interaction supports the notion of a closed loop...

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Bibliografiske detaljer
Main Authors: AMRANI, NADIA, GHOSH, SHUBHENDU, MANGUS, DAVID A., JACOBSON, ALLAN
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587346/
https://ncbi.nlm.nih.gov/pubmed/18496529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06974
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