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Classifying Variants of Undetermined Significance in BRCA2 with Protein Likelihood Ratios
BACKGROUND: Missense (aminoacid changing) variants found in cancer predisposition genes often create difficulties when clinically interpreting genetic testing results. Although bioinformatics has developed approaches to predicting the impact of these variants, many of these approaches have not been...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Libertas Academica
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587343/ https://ncbi.nlm.nih.gov/pubmed/19043619 |
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