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Production of Multimeric Prostate-Specific Membrane Antigen Small Molecule Radiotracers using a Solid-Phase (99m)Tc Pre-Loading Strategy

Small molecule ligands specific for prostate-specific membrane antigen (PSMA) have the potential to improve prostate cancer imaging. However, highly charged ligands are difficult to label with (99m)Tc and to purify. In this study, we present an adamantane-trimerized small molecule that has nanomolar...

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Bibliografiska uppgifter
Huvudupphovsmän: Misra, Preeti, Humblet, Valerie, Pannier, Nadine, Maison, Wolfgang, Frangioni, John V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587327/
https://ncbi.nlm.nih.gov/pubmed/17631555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.107.040303
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