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Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation

Declines in immune function are well described in the elderly, and are considered to contribute significantly to disease burden in this population. Regulatory T cells (T(regs)), a CD4(+) T cell subset usually characterized by high CD25 expression, control the intensity of immune responses, both in r...

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Autors principals: Lages, Celine S., Suffia, Isabelle, Velilla, Paula A., Huang, Bin, Warshaw, Gregg, Hildeman, David A., Belkaid, Yasmine, Chougnet, Claire
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587319/
https://ncbi.nlm.nih.gov/pubmed/18641321
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