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K(ATP) channel polymorphism is associated with left ventricular size in hypertensive individuals: a large-scale community-based study

ATP-sensitive K(+) (K(ATP)) channel mutations have been identified in individuals with dilated cardiomyopathy and overt heart failure. Here, a common E23K functional polymorphism in the Kir6.2 channel pore versus cardiac phenotype was studied in a cross-sectional community-based cohort (n = 2,031)....

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Detalhes bibliográficos
Main Authors: Reyes, Santiago, Terzic, Andre, Mahoney, Douglas W., Redfield, Margaret M., Rodeheffer, Richard J., Olson, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587318/
https://ncbi.nlm.nih.gov/pubmed/18504616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0519-3
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