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Effects of cations and osmotic protectants on cytolytic activity of Actinobacillus actinomycetemcomitans leukotoxin.

Actinobacillus actinomycetemcomitans leukotoxin permeabilized the plasma membrane of HL-60 promyelocytic leukemia cells, resulting in colloid osmotic lysis. These events were associated with efflux of 51chromium (from prelabeled cells), influx of propidium iodide, and ultrastructural evidence of cel...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Iwase, M, Lally, E T, Berthold, P, Korchak, H M, Taichman, N S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258723/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2341178/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.6.1782-1788.1990
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