Oxidative inactivation of Actinobacillus actinomycetemcomitans leukotoxin by the neutrophil myeloperoxidase system.

The leukotoxin of Actinobacillus actinomycetemcomitans has been implicated in the pathogenesis of inflammatory periodontal disease. We examined a potential mechanism for detoxification of this microbial product by the neutrophil myeloperoxidase system. Exposure to myeloperoxidase, H2O2, and a halide...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Clark, R A, Leidal, K G, Taichman, N S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.53.2.252-256.1986
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