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An ENU-induced mutation in the lymphotoxin α gene impairs lymph organogenesis of lymphoid tissues in C57BL/6 mice
The TNF family is critical for development of lymphoid organs and plays significant roles in regulation of innate and adoptive immune responses. Here we describe a novel N-ethyl-N-nitrosourea (ENU)-induced mutant strain, HLB382, with a point mutation in the Lta gene, which encodes lymphotoxin (LT) α...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587207/ https://ncbi.nlm.nih.gov/pubmed/18384745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.118 |
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