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Adipose is a conserved dosage-sensitive anti-obesity gene

Adipose (Adp) is an evolutionarily conserved gene isolated from naturally occurring obese flies homozygous for an adp mutation. Here we show that the anti-obesity function of Adp (worm Y73E7A.9, fly adp, and murine Wdtc1) is conserved from worms to mammals. Further, Adp appears to inhibit fat format...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suh, Jae Myoung, Zeve, Daniel, McKay, Renee, Seo, Jin, Salo, Zack, Li, Robert, Wang, Michael, Graff, Jonathan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587167/
https://ncbi.nlm.nih.gov/pubmed/17767906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.08.001
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