Estrogen receptor-positive mammary tumorigenesis in TGFα transgenic mice progresses with progesterone receptor loss

We characterized the novel NRL-transforming growth factor alpha (NRL-TGFα) transgenic mouse model in which growth factor - steroid receptor interactions were explored. The NRL promoter directs transgene expression to mammary ductal and alveolar cells and is nonresponsive to estrogen manipulations in...

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Autori principali: Rose-Hellekant, TA, Schroeder, MD, Brockman, JL, Zhdankin, O, Bolstad, R, Chen, KS, Gould, MN, Schuler, LA, Sandgren, EP
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587149/
https://ncbi.nlm.nih.gov/pubmed/17334393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210340
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