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Bioinformatics Assessment of β-Myosin Mutations Reveals Myosin High Sensitivity to Mutations

More than 200 mutations in the β-myosin gene (MYH7) that cause clinically distinct cardiac and/or skeletal myopathies have been reported, but to date no comprehensive statistical analysis of these mutations has been performed. As a part of this review, we developed a new interactive database and res...

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Autors principals: Buvoli, Massimo, Hamady, Micah, Leinwand, Leslie A., Knight, Rob
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587080/
https://ncbi.nlm.nih.gov/pubmed/18555187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2008.04.001
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