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Cutting Edge: Viral Infection Breaks NK Cell Tolerance to “Missing Self”
NK cells attack cells lacking MHC class I, yet MHC class I-deficient mice have normal numbers of NK cells with intact, albeit diminished, functions. Moreover, wild-type NK cells are tolerant of MHC class I-deficient cells in mixed bone marrow chimeras. Here, we investigated how the absence of MHC cl...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587071/ https://ncbi.nlm.nih.gov/pubmed/19017932 |
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