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Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide
Type I interferon (IFN) is crucial in host antiviral defense. Previous studies have described the pleiotropic role of type I IFNs on innate and adaptive immune cells during viral infection. Here, we demonstrate that natural killer (NK) cells from mice lacking the type I IFN-α receptor (Ifnar(−/−)) o...
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| Publicado en: | J Exp Med |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749923/ https://ncbi.nlm.nih.gov/pubmed/26755706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150712 |
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