TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation

Analogous to the clinical use of recombinant high-affinity antibodies, transfer of T cell receptor genes may be used to create a T cell compartment specific for self-antigens to which the endogenous T cell repertoire is immune tolerant. Here we show in a spontaneous prostate carcinoma model that the...

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Hlavní autoři: de Witte, Moniek A., Bendle, Gavin M., van den Boom, Marly D., Coccoris, Miriam, Schell, Todd D., Tevethia, Satvir S., van Tinteren, Harm, Mesman, Elly M., Song, Ji-Ying, Schumacher, Ton N.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587021/
https://ncbi.nlm.nih.gov/pubmed/18684947
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