Opioid Modulation of Extracellular Signal-Regulated Protein Kinase Activity Is Ras-Dependent and Involves G(βγ) Subunits

Although it is well-established that G protein-coupled receptor signaling systems can network with those of tyrosine kinase receptors by several mechanisms, the point(s) of convergence of the two pathways remains largely undelineated, particularly for opioids. Here we demonstrate that opioid agonist...

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Main Authors: Belcheva, Mariana M., Vogel, Zvi, Ignatova, Elena, Avidor-Reiss, Tomer, Zippel, Renata, Levy, Rivka, Young, Eric C., Barg, Jacob, Coscia, Carmine J.
Format: Artigo
Sprog:Inglês
Udgivet: 1998
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586992/
https://ncbi.nlm.nih.gov/pubmed/9453557
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