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κ-Opioid Agonist Modulation of [(3)H]Thymidine Incorporation into DNA: Evidence for the Involvement of Pertussis Toxin-Sensitive G Protein-Coupled Phosphoinositide Turnover

A body of evidence has indicated that μ-opioid agonists can inhibit DNA synthesis in developing brain. We now report that κ-selective opioid agonists (U69593 and U50488) modulate [(3)H]thymidine incorporation into DNA in fetal rat brain cell aggregates in a dose- and developmental stage-dependent ma...

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Библиографические подробности
Главные авторы: Barg, Jacob, Belcheva, Mariana Mancheva, Rowiński, Jan, Coscia, Carmine James
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586989/
https://ncbi.nlm.nih.gov/pubmed/8384252
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