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κ-Opioid Agonist Modulation of [(3)H]Thymidine Incorporation into DNA: Evidence for the Involvement of Pertussis Toxin-Sensitive G Protein-Coupled Phosphoinositide Turnover
A body of evidence has indicated that μ-opioid agonists can inhibit DNA synthesis in developing brain. We now report that κ-selective opioid agonists (U69593 and U50488) modulate [(3)H]thymidine incorporation into DNA in fetal rat brain cell aggregates in a dose- and developmental stage-dependent ma...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586989/ https://ncbi.nlm.nih.gov/pubmed/8384252 |
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