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Human SRY inhibits β-catenin-mediated transcription

In most mammals, sex is determined by the presence or absence of the SRY gene. SRY encodes a DNA binding HMG-box transcription factor which, during embryogenesis, is the initial trigger of testis differentiation from the bipotential gonad, yet its precise mode of function remains unclear. In ovarian...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bernard, Pascal, Sim, Helena, Knower, Kevin, Vilain, Eric, Harley, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586953/
https://ncbi.nlm.nih.gov/pubmed/18598779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.06.006
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