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Down-regulation of androgen-receptor and PSA by phytochemicals

The androgen receptor (AR) signaling pathway continues to be active in hormone resistant prostate cancer (HRPC) and can inappropriately activate transcription. Consequently the AR is a therapeutic target for HRPC. We reported that PC-SPES is active against HRPC, partly due to its actions in down-reg...

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Bibliographic Details
Main Authors: CHEN, SOPHIE, GAO, JIAN, HALICKA, H. DOROTA, TRAGANOS, FRANK, DARZYNKIEWICZ, ZBIGNIEW
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586941/
https://ncbi.nlm.nih.gov/pubmed/18202763
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