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Method for Screening and MALDI-TOF MS Sequencing of Encoded Combinatorial Libraries

We describe a new method for encoded synthesis, efficient on-resin screening, and rapid unambiguous sequencing of combinatorial peptide libraries. An improved binary tag system for encoding peptide libraries during synthesis was designed to facilitate unequivocal assignment of isobaric residues by M...

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Detalhes bibliográficos
Main Authors: Hu, Bi-Huang, Jones, Marsha Ritter, Messersmith, Phillip B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586901/
https://ncbi.nlm.nih.gov/pubmed/17713965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac070418g
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