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Method for Screening and MALDI-TOF MS Sequencing of Encoded Combinatorial Libraries

We describe a new method for encoded synthesis, efficient on-resin screening, and rapid unambiguous sequencing of combinatorial peptide libraries. An improved binary tag system for encoding peptide libraries during synthesis was designed to facilitate unequivocal assignment of isobaric residues by M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hu, Bi-Huang, Jones, Marsha Ritter, Messersmith, Phillip B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586901/
https://ncbi.nlm.nih.gov/pubmed/17713965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac070418g
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