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Adipocyte-derived Th2 cytokines and myeloid PPAR delta regulate macrophage polarization and insulin sensitivity
The polarization of adipose tissue resident macrophages towards the alternatively activated, anti-inflammatory M2 phenotype is believed to improve insulin sensitivity. However, mechanisms controlling tissue macrophage activation remain unclear. We show adipocytes are a source of Th2 cytokines, inclu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586840/ https://ncbi.nlm.nih.gov/pubmed/18522830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.04.002 |
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