A neuronal β subunit (KCNMB4) makes the large conductance, voltage- and Ca(2+)-activated K(+) channel resistant to charybdotoxin and iberiotoxin
Large conductance voltage and Ca(2+)-activated K(+) (MaxiK) channels couple intracellular Ca(2+) with cellular excitability. They are composed of a pore-forming α subunit and modulatory β subunits. The pore blockers charybdotoxin (CTx) and iberiotoxin (IbTx), at nanomolar concentrations, have been i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100118597 |
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