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Synthesis of 2,3-Disubstituted Benzo[b]furans by the Palladium-Catalyzed Coupling of o-Iodoanisoles and Terminal Alkynes, Followed by Electrophilic Cyclization
2,3-Disubstituted benzo[b]furans are readily prepared under very mild reaction conditions by the palladium/copper-catalyzed cross-coupling of various o-iodoanisoles and terminal alkynes, followed by electrophilic cyclization using I(2), PhSeCl or p-O(2)NC(6)H(4)SCl. Aryl- and vinylic-substituted alk...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586666/ https://ncbi.nlm.nih.gov/pubmed/16323837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo051299c |
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