Induction of intrachromosomal homologous recombination in human cells by raltitrexed, an inhibitor of thymidylate synthase

Thymidylate deprivation brings about “thymineless death” in prokaryotes and eukaryotes. Although the precise mechanism for thymineless death has remained elusive, inhibition of the enzyme thymidylate synthase (TS), which catalyzes the de novo synthesis of TMP, has served for many years as a basis fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Waldman, Barbara Criscuolo, Wang, Yibin, Kilaru, Kasturi, Yang, Zhengguan, Bhasin, Alaukik, Wyatt, Michael D., Waldman, Alan S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586641/
https://ncbi.nlm.nih.gov/pubmed/18603020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.06.006
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