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Improving peptide-MHC class I binding prediction for unbalanced datasets

BACKGROUND: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such binding could greatly reduce costs and accelerate the experimental process of identifying immunogenic peptides. Many methods...

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Main Authors: Sales, Ana Paula, Tomaras, Georgia D, Kepler, Thomas B
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586639/
https://ncbi.nlm.nih.gov/pubmed/18803836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-385
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