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Improved pan-specific MHC class I peptide binding predictions using a novel representation of the MHC binding cleft environment.

Major histocompatibility complex (MHC) molecules play a key roll in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in-silico methods have been developed to predict the binding affinity of a given peptide to a specific MHC molecule. One...

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Autors principals: Pro, Sebastian Carrasco, Zimic, Mirko, Nielsen, Morten
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925504/
https://ncbi.nlm.nih.gov/pubmed/24447175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tan.12292
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