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αE-catenin is not a significant regulator of β-catenin signaling in the developing mammalian brain
β-catenin is a critical mediator of the canonical Wnt signaling pathway. α-catenin is a major β-catenin binding protein and overexpressed α-catenin can negatively regulate β-catenin activity. Thus, α-catenin may be an important modulator of Wnt pathway. We show here that endogenous α-catenin has lit...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586592/ https://ncbi.nlm.nih.gov/pubmed/18397997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020537 |
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