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A Systematic Methodology for Defining Coarse-Grained Sites in Large Biomolecules

Coarse-grained (CG) models of biomolecules have recently attracted considerable interest because they enable the simulation of complex biological systems on length-scales and timescales that are inaccessible for atomistic molecular dynamics simulation. A CG model is defined by a map that transforms...

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Main Authors: Zhang, Zhiyong, Lu, Lanyuan, Noid, Will G., Krishna, Vinod, Pfaendtner, Jim, Voth, Gregory A.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586547/
https://ncbi.nlm.nih.gov/pubmed/18757560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.139626
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