NADPH Oxidase-dependent Generation of Lysophosphatidylserine Enhances Clearance of Activated and Dying Neutrophils via G2A

Exofacial phosphatidylserine (PS) is an important ligand mediating apoptotic cell clearance by phagocytes. Oxidation of PS fatty acyl groups (oxPS) during apoptosis reportedly mediates recognition through scavenger receptors. Given the oxidative capacity of the neutrophil NADPH oxidase, we sought to...

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Autori principali: Frasch, S. Courtney, Berry, Karin Zemski, Fernandez-Boyanapalli, Ruby, Jin, Hyun-Sun, Leslie, Christina, Henson, Peter M., Murphy, Robert C., Bratton, Donna L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Soggetti:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586279/
https://ncbi.nlm.nih.gov/pubmed/18824544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807047200
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