Pigment Epithelium-derived Factor Binds to Hyaluronan: MAPPING OF A HYALURONAN BINDING SITE

Pigment epithelium-derived factor (PEDF) is a multifunctional serpin with antitumorigenic, antimetastatic, and differentiating activities. PEDF is found within tissues rich in the glycosaminoglycan hyaluronan (HA), and its amino acid sequence contains putative HA-binding motifs. We show that PEDF co...

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Autors principals: Becerra, S. Patricia, Perez-Mediavilla, L. Alberto, Weldon, John E., Locatelli-Hoops, Silvia, Senanayake, Preenie, Notari, Luigi, Notario, Vicente, Hollyfield, Joe G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586245/
https://ncbi.nlm.nih.gov/pubmed/18805795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801287200
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