Pigment Epithelium-derived Factor (PEDF) Prevents Retinal Cell Death via PEDF Receptor (PEDF-R): IDENTIFICATION OF A FUNCTIONAL LIGAND BINDING SITE

The extracellular pigment epithelium-derived factor (PEDF) displays retina survival activity by interacting with receptor proteins on cell surfaces. We have previously reported that PEDF binds and stimulates PEDF receptor (PEDF-R), a transmembrane phospholipase. However, the PEDF binding site of PED...

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Autori principali: Subramanian, Preeti, Locatelli-Hoops, Silvia, Kenealey, Jason, DesJardin, Jacqueline, Notari, Luigi, Becerra, S. Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745339/
https://ncbi.nlm.nih.gov/pubmed/23818523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.487884
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