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Processive Movement by a Kinesin Heterodimer with an Inactivating Mutation in One Head

[Image: see text] A single molecule of the motor enzyme kinesin-1 keeps a tight grip on its microtubule track, making tens or hundreds of discrete, unidirectional 8 nm steps before dissociating. This high duty ratio processive movement is thought to require a mechanism in which alternating stepping...

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Autors principals: Thoresen, Todd, Gelles, Jeff
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2008
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586147/
https://ncbi.nlm.nih.gov/pubmed/18702529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800747e
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