HIV-1 Ribonuclease H Inhibitory Phenolic Glycosides from Eugenia hyemalis

Three new galloyl arbutins, hyemalosides A–C (1–3), along with nine known compounds were isolated from the evergreen tree Eugenia hyemalis. The structures of compounds 1–3 were determined by analysis of NMR and MS data. Compounds 1–3 inhibited HIV-1 RNase H in vitro with IC(50) values of 1.46, >1...

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Bibliographic Details
Main Authors: Bokesch, Heidi R., Wamiru, Antony, Le Grice, Stuart F. J., Beutler, John A., McKee, Tawnya C., McMahon, James B.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586124/
https://ncbi.nlm.nih.gov/pubmed/18763827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np8002518
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